Aerial parts, rhizome.
Though the herb has many proven beneficial effects on disorders such as varicose veins and hemorrhoids, it is not as widely used as it used to be before - the herb may soon regain its position as new evidence supports the remedial benefits attributed to it. The diuretic action and moderately laxative property of both the aerial shoots and the rhizome is attested in the herbal traditions of Europe, where the herb used to be extensively used in these roles in the folk medicine.
Many areas in Europe, western Asia, and North Africa have native populations of the butcher's broom and the plant is cultivated in some of these places. This herb grows in the wild on uncultivated and non agricultural lands as well as in woodlands, in many countries the butcher's broom is a protected species as wild varieties of the plant have become rare. The butcher's broom comes into fruit after the floral bloom in autumn, and the cultivated plants are gathered at this time - for processing, sorting and sale.
The ability to being about vasoconstriction possessed by an alcoholic extract of the butcher's-broom rhizomes was demonstrated in test animals during the course of a French investigation on the clinical ability of the rhizomes - underground stems, the extract brought about significant narrowing of blood vessels in all the test animals during the study. This property for vasoconstriction was due to the presence of mixtures of steroidal saponins in the extract, these active compounds were identified during further studies conducted on the rhizomes - the chemical compound ruscogenin and the compound neoruscogenin were identified as the two main saponins in the rhizome of the butcher's broom. These compounds seemed to directly affect the adrenergic receptors in the brain and the body, thus bringing about the vasoconstrictive effects in the test subjects. Further investigations on the butcher's broom rhizome has also been carried out in Japan, where the clinical researchers were able to isolate a total of twelve steroidal saponins from the herb, these compounds included seven new ones, and among these newly isolated saponins, significant cytostatic activity on leukemia HL-60 cells was found to be inducible by two of them. The beneficial effects and clinical significance of the herbal butcher's broom medication on venous disorders in humans have been given some support from the results derived in the limited clinical trials conducted on human test subjects. In other studies, the extracts of the butcher's broom have been observed to show some anti-inflammatory effects, along with their already confirmed vasoconstriction effects. The extracts of herbs such as the horse chestnut and witch hazel are marketed in many countries for their supposed beneficial effects on the venous circulation in humans, but European herbalist have increasingly started to believe that as far as these disorders are concerned, the butcher's broom extract may be much more effective than these other herbs in treating patients - this has come about partly due to the results from the studies conducted on the plant. The recognition of the potency of the butcher's broom extracts has resulted in the availability of commercially marketed butcher's broom extracts in the form of capsules, this is used in the treatment of circulatory problems affecting the legs, it is also used in the topical role as an ointment or herbal suppository to help alleviate the painful symptoms of hemorrhoids in affected patients.
The treatment of hemorrhoids is usually carried out using topical ointments and suppositories including those made from the butcher's broom herb in many countries. Patients typically apply or insert these in the affected area before sleeping at night. The treatment of systemic venous insufficiency in affected patients is usually carried out using the encapsulated butcher's broom extracts, which are sometimes combined with vitamin C or flavonoids and taken at 1000 mg thrice daily during the treatment period. If the encapsulated extract is not available, patients with venous insufficiency can also take 50-100 mg of standardized extract containing ruscogenins as a single dose on a daily basis.
The Food and Drug Administration still does not approve the medicinal use of the butcher's broom nor does it support any of the therapeutic benefits associated with this herb, since it has never been provided with proofs about its use as a therapeutic agent by the manufacturers of herbal products. For this reason, even when some basis for cautious optimism about the potentially medicinal benefits of the butcher's-broom exists, all would be consumers and patients must understand that all the therapeutic claims made for these products are illegal and have not been substantiated or proven. At the same time, it is inadvisable to use the butcher's broom remedy for circulatory disorders, or for that matter in treating any other potentially serious health problem, especially if this is carried out after self-diagnosis and the patient intends to self medicate - patients must always and without fail, consult a qualified doctor, whenever using herbal medicines, self-medication can be dangerous.